Diffuse Large B-cell Lymphoma Presenting with Obstructive Jaundice from a Biliary Stricture: A Case Report and Review of Literature

Diffuse large B cell lymphoma (DLBCL) is the most common histologic subtype of Non-Hodgkin’s lymphoma (NHL), accounting for approximately twenty five percent of cases. Forty percent of patients with DLBCL present with the primary lesion in an extranodal site. The gastrointestinal tract is the most frequent site of extranodal lymphoma, with the stomach and intestines most often involved. Involvement of the pancreas by NHL has been reported infrequently, and rarely does DLBCL present as obstructive jaundice from a biliary stricture or a pancreatic mass. The following report describes an unusual case of DLBCL of the pancreas presenting as obstructive jaundice from a biliary stricture.